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Lorena Anderson

Researchers Rebuild Microscopic Circadian Clock That Can Control Genes

Our circadian clocks play a crucial role in our health and well-being, keeping our 24-hour biological cycles in sync with light and dark exposure. Disruptions in the rhythms of these clocks, as with jet lag and daylight saving time, can throw our daily rhythms out of whack.

But a group of researchers is getting closer to understanding how these clocks operate.

UC Merced biochemistry Professor Andy LiWang and his colleagues have solved how the circadian clocks in microscopic bacteria precisely control when different genes are turned on and off during the 24-hour cycle.

Unlocking the Secrets of Tiny, Living Clocks Could Revolutionize Science

Biochemistry Professor Andy LiWang has spent much of his career studying how life keeps time. His work on the circadian clock of cyanobacteria — tiny, ancient organisms that share the planet with us — has shed light on one of biology’s most elegant systems.

But his newest research project, supported by a prestigious $1.2 million grant from the William M. Keck Foundation, pushes that inquiry into bold, uncharted territory.

UC Merced’s Berhe Joins Scientists in Warning of Global Land Mine Crisis

More than 100 million land mines remain buried around the world, posing a threat in approximately 70 countries and territories, and killing or injuring about 5,000 people, most of them civilians, every year. 

As the world’s geopolitical landscape shifts, nine scientists studying different aspects of warfare ecology from seven countries — Poland, Ukraine, Norway, Spain, the United States, Finland and Croatia — are warning against the growing deployment of land mines as countries bordering Russia withdraw from global conventions restricting their use.

LiWang’s Research into Biological Clocks Earns Protein Society Honors

Professor Andy LiWang knows what makes us tick, at least at a cellular level.

His research into the mechanisms of the oldest biological clock known to humankind has led him to understand how proteins — and hence cells — can tell time.

It has also led the UC Merced biochemist to become this year's recipient of the prestigious Dorothy Crowfoot Hodgkin award, sponsored by the Rigaku Corporation and given by The Protein Society (TPS).

Link Between Dementia and Air Pollution Drives Research Collaboration

California’s Central Valley, famous for producing much of the food Americans eat, is also infamous for its inferior air quality and its high rates of poverty, housing insecurity and at-risk workers.

Increasing epidemiological evidence has shown a correlation between long-term exposure to fine particulate matter (PM2.5) and the incidence of Alzheimer's disease and related dementias (ADRD).

Areas with severe PM2.5 pollution — including the Central Valley — are often inhabited by low-income residents who are disproportionately affected by these environmental hazards.

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